exFAT works just fine on mac and the OS uses APFS/HFS+.
For NTFS you can read but cannot write to it unless you get a 3rd party driver IIRC.
https://www.paragon-software.com/home/ntfs-mac/
Can read but, can I copy my files over to my mac?
Also can I copy a 25GB video file (as an example) to my mac and play it normally?