Oh yeah, you'll be fine - there's no real reason to go to the Tenderloin or Mid-Market anyway. You might find yourself on a streetcar through that part of town if you're on your way to the Castro, Dolores Park, or Golden Gate Park, but it's honestly fine - just something you'll pass on the way to the nicer parts of town.
Oh yeah. Anything around Union Square is fine - the Westin, the Hyatt Regency, or the Palace Hotel are all good picks. They're all close to Powell or Montgomery BART stations, as well - you want to be close to a BART station, because there's a direct BART train from the airport to the city.
Staying out in Fisherman's Wharf is more touristy, but it's also a lot more of a pain to get to, so you'll want to balance those two things.
This sounds like a really good plan.
>> Many thanks for these tips! In fact, will likely to follow the above and decide btw union square and fisherman's wharf.
I've used Turo, and... sometimes it's cheaper, but honestly it's a bit of a pain in the behind? I like just rocking up to the car rental place and driving off. (Pro tip: become a member of the car rental company's frequent driver program! At Hertz and Avis at least, if you're a member of their frequent-customer program you don't need to wait in the queue - you just go to the carpark, grab the car with your name on it, and go.)
>> Awesome, I'd go register
Hmm. Check out the
Glen Oaks, it's the least-extortionately-priced accommodation option around Big Sur. If they don't have accommodation, then your other options:
1) Carmel is very nice, but also very pricey;
2) Monterey is an
excellent option - it's more reasonably priced, and spending a night there is a great excuse to go to the aquarium. (If you're a Marriott loyalist, the Monterey Marriott is a perfectly good pick.)