High blood pressure: Why excess sugar in the diet may be the culprit
https://www.diabetes.co.uk/in-depth/high-blood-pressure-excess-sugar-diet-may-culprit/#:~:text=It is thought that when,and directly vasocontristing blood vessels.
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How Excess Sugar Causes High Blood Pressure
In order to effectively treat and recover from high blood pressure, it’s important to understand its underlying causes, which is often related to metabolic dysfunction in response to a high-carb and processed food diet:
#1:
Hyperinsulinemia
It is thought that when the body produces too much insulin and leptin in response to a higher-carb diet, it causes blood pressure to increase. Hyperinsulinemia raises blood pressure, in part, by decreasing sodium and water excretion in the kidneys, and directly vasocontristing blood vessels.
Hyperinsulinemia may play a direct role in atherogenesis and, by extensio,
atherosclerosis through the interaction of receptors on the blood vessel wall. Hyperinsulinemia is also known to alter lipid metabolism unfavourably, which promotes inflammation and oxidative stress.
#2:
Insulin resistance
As insulin levels rise, insulin resistance eventually develops. If insulin receptors are blunted and the cells grow resistant to insulin, magnesium can no longer be stored, so it passes out of the body through urination. When magnesium levels are too low, blood vessels are unable to fully relax, and this constriction raises blood pressure.
#3:
Nitric oxide
Fructose sugar, specifically, elevates uric acid, which drives up blood pressure by inhibiting the nitric oxide (NO) in blood vessels. NO is regarded as the most important vasodilator and helps blood vessels maintain their elasticity. NO suppression leads to increases in blood pressure.
#4:
Advanced glycation
Advanced glycation end products (AGEs) are the direct result of exposure to sugars. This is one of the major pathway involved in the development and progression of different diabetes-related complications. They are believed to play a role in vascular complications by triggering processes that cause vascular stiffening and the narrowing of blood vessels, contributing to atherosclerosis.
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